Tomatoes, potatos, peppers, corn, tobacco, peanuts, chocolate, vanilla, squash, pumpkin, zucchini, and sunflowers are all native to the Americas, and did not exist in the rest of the world before Columbus.

According to the United States Department of Agriculture, rapeseed was the third leading source of vegetable oil in the world in 2000, after soybean and oil palm.

Vanilla flowers may only be naturally pollinated by a specific bee found in Mexico. Vanilla grown elsewhere must have each flower individually pollinated by human workers.

Vanilla planifolia seeds will not germinate in normal ground; they need a certain symbiotic mushroom.

The grapefruit is a hybrid between the pomelo and the orange.